Warren S. Warren
James B. Duke Distinguished Professor of Chemistry
Professor of Chemistry
Professor of Radiology (Joint)
Professor of Physics (Joint)
Member of the Duke Cancer Institute
Our work focuses on the design and application of what might best be called novel pulsed techniques, using controlled radiation fields to alter dynamics. The heart of the work is chemical physics, and most of what we do is ultrafast laser spectroscopy or nuclear magnetic resonance. It generally involves an intimate mixture of theory and experiment: recent publications are roughly an equal mix of pencil- and-paper theory, computer calculations with our workstations, and experiments. Collaborations also play an important role, particularly for medical applications.
Robles, Francisco E., et al. “Pump-probe imaging of pigmented cutaneous melanoma primary lesions gives insight into metastatic potential.” Biomed Opt Express, vol. 6, no. 9, Sept. 2015, pp. 3631–45. Pubmed, doi:10.1364/BOE.6.003631. Full Text
Davis, Ryan M., and Warren S. Warren. “Intermolecular zero quantum coherences enable accurate temperature imaging in red bone marrow.” Magnetic Resonance in Medicine, vol. 74, no. 1, July 2015, pp. 63–70. Epmc, doi:10.1002/mrm.25372. Full Text
Crumbliss, Alvin L., et al. “Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA.” Biometals, vol. 28, no. 3, June 2015, p. 431. Pubmed, doi:10.1007/s10534-015-9854-8. Full Text
Wilson, Jesse W., et al. “Comparing in vivo pump-probe and multiphoton fluorescence microscopy of melanoma and pigmented lesions.” J Biomed Opt, vol. 20, no. 5, May 2015, p. 051012. Pubmed, doi:10.1117/1.JBO.20.5.051012. Full Text
Shchepin, Roman V., et al. “Hyperpolarization of "Neat" Liquids by NMR Signal Amplification by Reversible Exchange.” The Journal of Physical Chemistry Letters, vol. 6, no. 10, May 2015, pp. 1961–67. Epmc, doi:10.1021/acs.jpclett.5b00782. Full Text
Truong, Milton L., et al. “15N Hyperpolarization by Reversible Exchange Using SABRE-SHEATH.” The Journal of Physical Chemistry. C, Nanomaterials and Interfaces, vol. 119, no. 16, Apr. 2015, pp. 8786–97. Epmc, doi:10.1021/acs.jpcc.5b01799. Full Text
Wilson, Jesse W., et al. “Flexible digital signal processing architecture for narrowband and spread-spectrum lock-in detection in multiphoton microscopy and time-resolved spectroscopy.” Review of Scientific Instruments, vol. 86, no. 3, AIP Publishing, Mar. 2015, pp. 033707–033707. Crossref, doi:10.1063/1.4916261. Full Text
Theis, Thomas, et al. “Microtesla SABRE enables 10% nitrogen-15 nuclear spin polarization.” Journal of the American Chemical Society, vol. 137, no. 4, Feb. 2015, pp. 1404–07. Epmc, doi:10.1021/ja512242d. Full Text
Theis, Thomas, et al. “LIGHT-SABRE enables efficient in-magnet catalytic hyperpolarization.” Journal of Magnetic Resonance (San Diego, Calif. : 1997), vol. 248, Nov. 2014, pp. 23–26. Epmc, doi:10.1016/j.jmr.2014.09.005. Full Text
Claytor, Kevin, et al. “Accessing long-lived disconnected spin-1/2 eigenstates through spins > 1/2.” Journal of the American Chemical Society, vol. 136, no. 43, Oct. 2014, pp. 15118–21. Epmc, doi:10.1021/ja505792j. Full Text
Matthews, T. E., et al. “Beyond Pathology: Pump-probe imaging of skin slices provides additional indicators of melanoma.” Optics Infobase Conference Papers, 2011.
Samineni, P., et al. “Nonlinear phase contrast imaging in neuronal tissue.” Optics Infobase Conference Papers, 2011.
Samineni, P., et al. “Nonlinear phase contrast imaging in neuronal tissue.” Optics Infobase Conference Papers, Optical Society of America, 2011.
Li, B., et al. “Optimizing shape of femtosecond laser pulses for homodyne detection of nonlinear optical signals.” Optics Infobase Conference Papers, 2011. Scopus, doi:10.1364/fio.2011.ftuq5. Full Text
Samineni, P., et al. “Nonlinear phase contrast imaging in neuronal tissue.” Optics Infobase Conference Papers, 2011. Scopus, doi:10.1364/ntm.2011.nmd3. Full Text
Li, B., et al. “Enhancing coherent anti-stokes Raman scattering background suppression with phase cycled structured femtosecond laser pulses.” Optics Infobase Conference Papers, 2010.
Samineni, P., et al. “Femtosecond laser pulse shaping improves self-phase modulation measurements in scattering media.” Optics Infobase Conference Papers, 2010.
Warren, W. S., et al. “Nonlinear microscopy without fluorescence: Seeing the needle in the Haystack with Femtosecond pulse shaping.” Optics Infobase Conference Papers, 2009.
Fischer, M. C., et al. “Enhancing two-color absorption, self-phase modulation and raman microscopy signatures in tissue with femtosecond laser pulse shaping.” Progress in Biomedical Optics and Imaging Proceedings of Spie, vol. 7183, 2009. Scopus, doi:10.1117/12.816488. Full Text