Professor of Mechanical Engineering and Materials Science
Professor of Biomedical Engineering (Joint)
Professor of Physics (Joint)
Professor of Chemistry (Joint)
The research of the Rubinstein group is in the field of polymer theory and computer simulations. The unique properties of polymeric systems are due to the size, topology and interactions of the molecules they are made of. Our goal is to understand the properties of various polymeric systems and to design new systems with even more interesting and useful properties.
Our approach is based upon building and solving simple molecular models of different polymeric systems. The models we develop are simple enough to be solved either analytically or numerically, but contain the main features leading to unique properties of real polymers. Computer simulations of our models serve as an important bridge between analytical calculations and experiments.
Engineering Technologies to Determine Causal Relationships Between Chromatin Structure and Gene Regulation awarded by National Science Foundation (Co-Principal Investigator). 2018 to 2022
Center for the Chemistry of Molecularly Optimized Networks awarded by National Science Foundation (Co Investigator). 2018 to 2021
Collaborative Research: RAPID: Augmenting Mucosal Gels with Associating Brush Polymers to Prevent COVID19 Infection awarded by National Science Foundation (Co Investigator). 2020 to 2021
Development of Novel Mycolytic Therapies for Lung Disease, Project 1: Mechanism of action of mucolytics in improving mucus clearance in lung disease awarded by University of North Carolina - Chapel Hill (Principal Investigator). 2019 to 2020
Development of Novel Mycolytic Therapies for Lung Disease, Project 1: Mechanism of action of mucolytics in improving mucus clearance in lung disease awarded by University of North Carolina - Chapel Hill (Principal Investigator). 2018 to 2019
Huang, Q., et al. “Unexpected Stretching of Entangled Ring Macromolecules.” Physical Review Letters, vol. 122, no. 20, May 2019, p. 208001. Epmc, doi:10.1103/physrevlett.122.208001. Full Text
Wang, S., et al. “Quantitative Adjustment to the Molecular Energy Parameter in the Lake-Thomas Theory of Polymer Fracture Energy.” Macromolecules, vol. 52, no. 7, Apr. 2019, pp. 2772–77. Scopus, doi:10.1021/acs.macromol.8b02341. Full Text
Galati, Elizabeth, et al. “Helicoidal Patterning of Nanorods with Polymer Ligands.” Angewandte Chemie (International Ed. in English), vol. 58, no. 10, Mar. 2019, pp. 3123–27. Epmc, doi:10.1002/anie.201812887. Full Text
Ge, Ting, and Michael Rubinstein. “Mobility of Polymer-Tethered Nanoparticles in Unentangled Polymer Melts.” Macromolecules, vol. 52, no. 4, Feb. 2019, pp. 1536–45. Epmc, doi:10.1021/acs.macromol.8b02138. Full Text
Button, Brian, et al. “Roles of mucus adhesion and cohesion in cough clearance.” Proceedings of the National Academy of Sciences of the United States of America, vol. 115, no. 49, Dec. 2018, pp. 12501–06. Epmc, doi:10.1073/pnas.1811787115. Full Text
Rubinstein, Michael, et al. “Structure of Liquid Coacervates formed by Oppositely Charged Polyelectrolytes.” Macromolecules, vol. 51, no. 23, Dec. 2018, pp. 9572–88. Epmc, doi:10.1021/acs.macromol.8b02059. Full Text
Shi, Ran, et al. “Elastic-Plastic Transformation of Polyelectrolyte Complex Hydrogels from Chitosan and Sodium Hyaluronate.” Macromolecules, vol. 51, no. 21, Nov. 2018, pp. 8887–98. Epmc, doi:10.1021/acs.macromol.8b01658. Full Text
Zhou, Jinsheng, et al. “Enhanced nanochannel translocation and localization of genomic DNA molecules using three-dimensional nanofunnels.” Nature Communications, vol. 8, no. 1, Springer Science and Business Media LLC, Dec. 2017. Crossref, doi:10.1038/s41467-017-00951-4. Full Text
Lopez, Gabriel, et al. “Programming molecular self-assembly of intrinsically disordered proteins.” Abstracts of Papers of the American Chemical Society, vol. 251, AMER CHEMICAL SOC, 2016.
Rubinstein, Michael. “Polymer physics-The ugly duckling story: Will polymer physics ever become a part of “proper” physics?” Journal of Polymer Science Part B: Polymer Physics, vol. 48, no. 24, Wiley, 2010, pp. 2548–51. Crossref, doi:10.1002/polb.22135. Full Text
Rubinstein, Michael, and Audrey V. Dobrynin. “Associations leading to formation of reversible networks and gels.” Current Opinion in Colloid & Interface Science, vol. 4, no. 1, Elsevier BV, Feb. 1999, pp. 83–87. Crossref, doi:10.1016/s1359-0294(99)00013-8. Full Text