Glenn S. Edwards

Professor of Physics

Office Location: 
French Family Science Center, 2314, Durham, NC 27708
Front Office Address: 
Box 90305, Durham, NC 27708-0305
Phone: 
(919) 660-2674

Overview

Glenn Edwards investigates biological systems using a range of experimental techniques and theoretical methods from physics. His interests include Investigations of energy transduction where laser energy transforms into vibrational energy of biological molecules which then transforms into heat and pressure pulses that selectively drive tissue-scale dynamics. This line of research has led to human surgical applications of Free-Electron Lasers and spin-off laser technology. Another interest includes investigations of how biology harnesses physical mechanisms in biomechanical processes. This line of research investigates tissue dynamics and pattern formation during early development in Drosophila embryos.

Education & Training

  • Ph.D., University of Maryland, College Park 1984

  • B.S., University of Maryland, College Park 1978

Selected Grants

Morphogenesis: Biophysics and Genetics of Dorsal Closure awarded by National Institutes of Health (Co Investigator). 1984 to 2018

Complex Networks: Structure and Function of Large-Scale Neural Networks awarded by Army Research Office (Principal Investigator). 2012 to 2015

Structural Biology and Biophysics Training Program awarded by National Institutes of Health (Mentor). 1994 to 2015

Complex Networks Response to Excitations awarded by Army Research Office (Principal Investigator). 2007 to 2010

Biomedical and Biological Research Applications of a Storage-Ring Free-Electron Laser awarded by Air Force Office of Scientific Research (Principal Investigator). 2000 to 2008

Mathematical Analysis of Non-Stationary Fluctuations awarded by Army Research Office (Principal Investigator). 2003 to 2007

Novel Research Opportunities Using the Duke Storage-Ring FEL awarded by Air Force Office of Scientific Research (Principal Investigator). 2004 to 2006

Center for FEL Research in the Medical, Biological, and Materials Sciences awarded by Air Force Office of Scientific Research (Principal Investigator). 2000 to 2001

Biophysical Research at the Duke FEL Laboratory awarded by Office of Naval Research (Principal Investigator). 1999 to 2000

Infrastructure Support for Light Sources at the Duke FEL Laboratory awarded by Office of Naval Research (Principal Investigator). 1994 to 2000

Pages

Kiehart, DP, Crawford, JM, Aristotelous, A, Venakides, S, and Edwards, GS. "Cell Sheet Morphogenesis: Dorsal Closure in Drosophila melanogaster as a Model System." Annual review of cell and developmental biology 33 (October 2017): 169-202. Full Text

Lu, H, Sokolow, A, Kiehart, DP, and Edwards, GS. "Quantifying dorsal closure in three dimensions." Molecular biology of the cell 27.25 (December 2016): 3948-3955. Full Text

Lu, H, Sokolow, A, Kiehart, DP, and Edwards, GS. "Remodeling Tissue Interfaces and the Thermodynamics of Zipping during Dorsal Closure in Drosophila." Biophysical Journal 109.11 (December 2015): 2406-2417. Full Text

Wells, AR, Zou, RS, Tulu, US, Sokolow, AC, Crawford, JM, Edwards, GS, and Kiehart, DP. "Complete canthi removal reveals that forces from the amnioserosa alone are sufficient to drive dorsal closure in Drosophila." Molecular biology of the cell 25.22 (November 2014): 3552-3568. Full Text

Sokolow, A, Toyama, Y, Kiehart, DP, and Edwards, GS. "Cell ingression and apical shape oscillations during dorsal closure in Drosophila." Biophys J 102.5 (March 7, 2012): 969-979. Full Text

Layton, AT, Toyama, Y, Yang, G-Q, Edwards, GS, Kiehart, DP, and Venakides, S. "Drosophila morphogenesis: tissue force laws and the modeling of dorsal closure." HFSP J 3.6 (December 2009): 441-460. Full Text

Bush, WD, Garguilo, J, Zucca, FA, Bellei, C, Nemanich, RJ, Edwards, GS, Zecca, L, and Simon, JD. "Neuromelanins isolated from different regions of the human brain exhibit a common surface photoionization threshold." Photochem Photobiol 85.1 (January 2009): 387-390. Full Text

Wagner, W, Sokolow, A, Pearlstein, R, and Edwards, G. "Thermal Vapor Bubble and Pressure Dynamics During Infrared Laser Ablation of Tissue." Applied Physics Letters 94.013901 (2009). (Academic Article)

Layton, AT, Toyama, Y, Yang, G-Q, Edwards, GS, Kiehart, DP, and Venakides, S. "Drosophila Morphogenesis: Tissue Force Laws and the Modeling of Dorsal Closure." Human Frontier Science Program Journal 3.6 (2009): doi:10.2976/1.3266062-. (Academic Article)

Pages