G. Allan Johnson

G. Allan Johnson

Charles E. Putman University Professor of Radiology

Office Location: 
141D Bryan Neuroscience Bldg, Research Drive, Durham, NC 27710
Front Office Address: 
Box 3302 Med Ctr, Durham, NC 27710
Phone: 
(919) 684-7754
Office Hours: 
8:30 AM-5:00 PM and by appointment.

Overview

Dr. Johnson is the Charles E. Putman University Professor of Radiology, Professor of Physics, and Biomedical Engineering, and Director of the Duke Center for In Vivo Microscopy (CIVM). The CIVM is an NIH/NIBIB national Biomedical Technology Resource Center with a mission to develop novel technologies for preclinical imaging (basic sciences) and apply the technologies to critical biomedical questions. Dr. Johnson was one of the first researchers to bring Paul Lauterbur's vision of magnetic resonance (MR) microscopy to practice as described in his paper, "Nuclear magnetic resonance imaging at microscopic resolution" (J Magn Reson 68:129-137, 1986). Dr. Johnson is involved in both the engineering physics required to extend the resolution of MR imaging and in a broad range of applications in the basic sciences.

Education & Training

  • Ph.D., Duke University 1974

Selected Grants

The Duke Preclinical Research Resources for Quantitative Imaging Biomarkers awarded by National Institutes of Health (PD/PI). 2017 to 2022

The Duke Preclinical Research Resources for Quantitative Imaging Biomarkers awarded by National Institutes of Health (Co-Principal Investigator). 2017 to 2022

Transmission electron microscope (TEM) awarded by National Institutes of Health (Major User). 2019 to 2020

Neuronal Networks in Traumatic Brain Injury of ApoE Mice awarded by (Principal Investigator). 2019

Waxholm Space for Rodent Neuroinformatics awarded by University of Pennsylvania (Principal Investigator). 2016 to 2019

Training in Medical Imaging awarded by National Institutes of Health (Mentor). 2003 to 2019

Quantitative MR Microscopy of Phenotypic Biomarkers in Alzheimer's Disease awarded by National Institutes of Health (Mentor). 2013 to 2018

Integrated Center For In Vivo Microscopy awarded by National Institutes of Health (Principal Investigator). 2003 to 2018

Serial Block Face Scanning Electron Microscope awarded by National Institutes of Health (Major User). 2016 to 2018

Ultra-resolution imaging of brain circuitry and its development in mental health awarded by National Institutes of Health (Co Investigator). 2013 to 2016

Pages

Paxinos, G., et al. An MRI/DTI Atlas of the Rat Brain. Elsevier, Academic Press, 2015.

Spiliopoulos, D., et al. “Digital Subtracted Angiography of Small Animals.” Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications, edited by G. C. Kagadis et al., Taylor & Francis Books, Inc., CRC Press, 2016, pp. 67–75.

Zhou, X., and G. A. Johnson. “Magnetic resonance microscopy.” Medical Imaging: Principles and Practices, 2012. Scopus, doi:10.1201/b12939. Full Text

Zhou, X., and G. A. Johnson. “Magnetic resonance microscopy.” Medical Devices and Systems, 2006.

Zhou, X., and G. Allan Johnson. “Magnetic resonance microscopy.” Biomedical Imaging, 2003.

Allan Johnson, G., et al. “Whole mouse brain connectomics..” J Comp Neurol, vol. 527, no. 13, Sept. 2019, pp. 2146–57. Pubmed, doi:10.1002/cne.24560. Full Text

Anderson, Robert J., et al. “Small Animal Multivariate Brain Analysis (SAMBA) - a High Throughput Pipeline with a Validation Framework..” Neuroinformatics, vol. 17, no. 3, July 2019, pp. 451–72. Pubmed, doi:10.1007/s12021-018-9410-0. Full Text

Wang, Nian, et al. “Diffusion tractography of the rat knee at microscopic resolution..” Magn Reson Med, vol. 81, no. 6, June 2019, pp. 3775–86. Pubmed, doi:10.1002/mrm.27652. Full Text

Privratsky, Jamie R., et al. “Dynamic contrast-enhanced MRI promotes early detection of toxin-induced acute kidney injury..” Am J Physiol Renal Physiol, vol. 316, no. 2, Feb. 2019, pp. F351–59. Pubmed, doi:10.1152/ajprenal.00416.2018. Full Text

Wang, Nian, et al. “Accelerating quantitative susceptibility imaging acquisition using compressed sensing..” Phys Med Biol, vol. 63, no. 24, Dec. 2018. Pubmed, doi:10.1088/1361-6560/aaf15d. Full Text

Wang, Nian, et al. “Whole mouse brain structural connectomics using magnetic resonance histology..” Brain Struct Funct, vol. 223, no. 9, Dec. 2018, pp. 4323–35. Pubmed, doi:10.1007/s00429-018-1750-x. Full Text

Nouls, John C., et al. “Diffusion tensor imaging using multiple coils for mouse brain connectomics..” Nmr Biomed, vol. 31, no. 6, June 2018. Pubmed, doi:10.1002/nbm.3921. Full Text

Calabrese, Evan, et al. “Postmortem diffusion MRI of the entire human spinal cord at microscopic resolution..” Neuroimage Clin, vol. 18, 2018, pp. 963–71. Pubmed, doi:10.1016/j.nicl.2018.03.029. Full Text

Wei, Hongjiang, et al. “Susceptibility tensor imaging and tractography of collagen fibrils in the articular cartilage..” Magn Reson Med, vol. 78, no. 5, Nov. 2017, pp. 1683–90. Pubmed, doi:10.1002/mrm.26882. Full Text

Vetreno, Ryan P., et al. “Adult rat cortical thickness changes across age and following adolescent intermittent ethanol treatment..” Addict Biol, vol. 22, no. 3, May 2017, pp. 712–23. Pubmed, doi:10.1111/adb.12364. Full Text

Pages

Johnson, G. A., et al. “Image-processing pipelines: Applications in magnetic resonance histology.” Progress in Biomedical Optics and Imaging  Proceedings of Spie, vol. 9784, 2016. Scopus, doi:10.1117/12.2203525. Full Text

Calabrese, E., et al. “Postmortem Diffusion MRI of the Human Brainstem and Thalamus for Deep Brain Stimulator Electrode Localization.” Movement Disorders, vol. 30, no. 10, WILEY-BLACKWELL, 2015, pp. E6–E6.

Johnson, G. Allan, et al. “Magnetic resonance histology—Applications in toxicology.” Toxicology Letters, vol. 229, Elsevier BV, 2014, pp. S31–32. Crossref, doi:10.1016/j.toxlet.2014.06.148. Full Text

Clark, D. P., et al. “A multi-resolution approach to retrospectively-gated cardiac micro-CT reconstruction.” Progress in Biomedical Optics and Imaging  Proceedings of Spie, vol. 9033, 2014. Scopus, doi:10.1117/12.2043044. Full Text

Clark, D. P., et al. “Robust material decomposition for spectral CT.” Progress in Biomedical Optics and Imaging  Proceedings of Spie, vol. 9038, 2014. Scopus, doi:10.1117/12.2042546. Full Text

Badea, C. T., et al. “Dual-energy micro-CT imaging of pulmonary airway obstruction: Correlation with micro-SPECT.” Progress in Biomedical Optics and Imaging  Proceedings of Spie, vol. 9038, 2014. Scopus, doi:10.1117/12.2043094. Full Text

Johnston, S. M., et al. “Helical dual source cone-beam micro-CT.” 2014 Ieee 11th International Symposium on Biomedical Imaging, Isbi 2014, 2014, pp. 177–80.

Clark, D., et al. “The effect of scatter correction on dual energy micro-CT.” Progress in Biomedical Optics and Imaging  Proceedings of Spie, vol. 8668, 2013. Scopus, doi:10.1117/12.2006904. Full Text

Parnell, S. E., et al. “EFFECTS OF CHRONIC EARLY GESTATIONAL ETHANOL EXPOSURE ON THE DEVELOPING BRAIN: A MAGNETIC RESONANCE MICROSCOPY STUDY.” Alcoholism Clinical and Experimental Research, vol. 36, 2012, pp. 279A-279A.

Guo, X., et al. “A comparison of sampling strategies for dual energy micro-CT.” Progress in Biomedical Optics and Imaging  Proceedings of Spie, vol. 8313, 2012. Scopus, doi:10.1117/12.911548. Full Text

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