Ehsan Samei

Professor of Radiology

Office Location: 
2424 Erwin Road, Suite 302, Ravin Advanced Imaging Labs, Durham, NC 27705
Front Office Address: 
DUMC Box 2731, Durham, NC 27710
(919) 684-7852


Dr. Ehsan Samei, PhD, DABR, FAAPM, FSPIE is a tenured Professor of Radiology, Medical Physics, Biomedical Engineering, Physics, and Electrical and Computer Engineering at Duke University, where he also serves as the Director of Carl E. Ravin Advanced Imaging Laboratories and the founding Chief of the Clinical Imaging Physics Group. He is certified by the American Board of Radiology, and is a Fellow of the American Association of Physicists in Medicine (AAPM), and the International Society of Optical Engineering (SPIE). He was the founding Director of the Graduate Studies of the Duke Medical Physics Graduate Program, and the co-founder of the Society of Directors of Academic Medical Physics Programs (SDAMPP). He has held senior leadership positions in the AAPM, the SPIE, and SDAMPP. He is a Councilor of the National Council of Radiation Protection and Measurements (NCRP), and a Distinguished Investigator of the Academy of Radiology Research.

Dr. Samei’s interests and expertise include x-ray imaging, theoretical imaging models, simulation methods, and experimental techniques in medical image formation, analysis, assessment, display, and perception. His current research includes methods to develop image quality and dose metrics that are clinically relevant and that can be used to design and utilize advanced imaging techniques towards precise interpretive and quantitative performance. He further has an active interest in bridging the gap between scientific scholarship and clinical practice, in the meaningful realization of translational research and in clinical processes that are informed by scientific evidence. While he works across most diagnostic imaging modalities, his main modalities of interest are CT and Tomosynthesis for breast, lung, and abdominal imaging applications. He has been the recipient of 29 extramural grants from the US government, private foundations, and medical industry, and has 700 scientific publications including 190 referred journal articles.

Education & Training

  • Ph.D., University of Michigan at Ann Arbor 1997

  • M.E., University of Michigan at Ann Arbor 1995

Selected Grants

Precision Cardiac CT: Development of a Computational Platform for Optimizing Imaging awarded by National Institutes of Health (Principal Investigator). 2017 to 2021

Physics Associates Affiliate Residency Program awarded by Physics Associates (Principal Investigator). 2017 to 2020

Training in Medical Imaging awarded by National Institutes of Health (Mentor). 2003 to 2019

Simulation Tools for 3D and 4D CT and Dosimetry awarded by National Institutes of Health (Co-Principal Investigator). 2007 to 2018

Imaging Physics Residency Grant awarded by American Association of Physicists in Medicine (Principal Investigator). 2014 to 2018

Reconstruction Software Evaluation awarded by Siemens Medical Solutions USA, Inc. (Principal Investigator). 2014 to 2018

Methodology and Reference Image set for Volumetric Characterization and Compliance awarded by Radiological Society of North America (Principal Investigator). 2014 to 2017

Reference Image Set for Quantitation Conformance of Algorithmic Lesion Characterization awarded by Radiological Society of North America (Principal Investigator). 2014 to 2017

Advancement and Effective Implementation of Dose and Risk Monitoring Systems awarded by GE Healthcare (Principal Investigator). 2014 to 2017

Decreased Variability for Robust Imaging-based Quantification of Tumor Heterogeneity awarded by Radiological Society of North America (Advisor). 2015 to 2017


Samei, E, Tian, X, Paul Segars, W, and Frush, DP. "Radiation risk index for pediatric CT: a patient-derived metric." Pediatric radiology 47.13 (December 2017): 1737-1744. Full Text

Abadi, E, Sahbaee, P, and Samei, E. "Effect of Iodine-based Contrast Material on Radiation Dose at CT." Radiology 285.3 (December 2017): 1053-1054. Full Text

Fu, W, Marin, D, Ramirez-Giraldo, JC, Choudhury, KR, Solomon, J, Schabel, C, Patel, BN, and Samei, E. "Optimizing window settings for improved presentation of virtual monoenergetic images in dual-energy computed tomography." Medical physics 44.11 (November 2017): 5686-5696. Full Text

Winslow, J, Zhang, Y, and Samei, E. "A method for characterizing and matching CT image quality across CT scanners from different manufacturers." Medical physics 44.11 (November 2017): 5705-5717. Full Text

Ria, F, Bergantin, A, Vai, A, Bonfanti, P, Martinotti, AS, Redaelli, I, Invernizzi, M, Pedrinelli, G, Bernini, G, Papa, S, and Samei, E. "Awareness of medical radiation exposure among patients: A patient survey as a first step for effective communication of ionizing radiation risks." Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) 43 (November 2017): 57-62. Full Text Open Access Copy

Robins, M, Solomon, J, Sahbaee, P, Sedlmair, M, Roy Choudhury, K, Pezeshk, A, Sahiner, B, and Samei, E. "Techniques for virtual lung nodule insertion: volumetric and morphometric comparison of projection-based and image-based methods for quantitative CT." Physics in medicine and biology 62.18 (August 8, 2017): 7280-7299. Full Text

Samei, E, Li, X, and Frush, DP. "Size-based quality-informed framework for quantitative optimization of pediatric CT." Journal of medical imaging (Bellingham, Wash.) 4.3 (July 2017): 031209-. Full Text

Fu, W, Sturgeon, GM, Agasthya, G, Segars, WP, Kapadia, AJ, and Samei, E. "Breast dose reduction with organ-based, wide-angle tube current modulated CT." Journal of medical imaging (Bellingham, Wash.) 4.3 (July 2017): 031208-. Full Text


Robins, M, Solomon, J, Hoye, J, Smith, T, Ebner, L, and Samei, E. "Inter-algorithm lesion volumetry comparison of real and 3D simulated lung lesions in CT." January 1, 2017. Full Text

Zhao, C, Solomon, J, Sturgeon, GM, Gehm, ME, Catenacci, M, Wiley, BJ, Samei, E, and Lo, JY. "Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region." January 1, 2017. Full Text

Hoye, J, Zhang, Y, Agasthya, G, Sturgeon, G, Kapadia, A, Segars, WP, and Samei, E. "An atlas-based organ dose estimator for tomosynthesis and radiography." January 1, 2017. Full Text

Fu, W, Sturgeon, GM, Agasthya, G, Segars, WP, Kapadia, AJ, and Samei, E. "Estimation of breast dose reduction potential for organ-based tube current modulated CT with wide dose reduction arc." January 1, 2017. Full Text

Abadi, E, Sturgeon, GM, Agasthya, G, Harrawood, B, Hoeschen, C, Kapadia, A, Segars, WP, and Samei, E. "Airways, vasculature, and interstitial tissue: Anatomically informed computational modeling of human lungs for virtual clinical trials." January 1, 2017. Full Text

Zheng, Y, Solomon, J, Choudhury, K, Marin, D, and Samei, E. "Accuracy and variability of texture-based radiomics features of lung lesions across CT imaging conditions." January 1, 2017. Full Text