Bastiaan Driehuys

Bastiaan Driehuys

Professor of Radiology

Professor of Physics (Secondary)

Professor in the Department of Biomedical Engineering (Secondary)

Office Location: 
161-B Bryan Research, 311 Research Drive, Durham, NC 27710
Front Office Address: 
Box 3302 Med Ctr, Durham, NC 27710
(919) 684-7786


My research program is focused on developing and applying hyperpolarized gases to enable fundamentally new applications in MRI. Currently we use this technology to non-invasively image pulmonary function in 3D. Hyperpolarization involves aligning nuclei to a high degree to enhance their MRI signal by 5-6 orders of magnitude. Thus, despite the low density of gases relative to water (the ordinary signal source in MRI), they can be imaged at high-resolution in a single breath. This technology leads to a host of interesting areas of study including: investigating the basic physics of hyperpolarization, developing new MR methods and hardware for image acquisition, image analysis and quantification, and of, course applying this technology to a host of chronic diseases including, asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis.

Education & Training

  • Ph.D., Princeton University 1995

Albert, M. S., et al. “Biological magnetic resonance imaging using laser-polarized 129Xe.Nature, vol. 370, no. 6486, July 1994, pp. 199–201. Pubmed, doi:10.1038/370199a0. Full Text

Barton, A. S., et al. “Self-calibrating measurement of polarization-dependent frequency shifts from Rb-3He collisions.Phys Rev A, vol. 49, no. 4, Apr. 1994, pp. 2766–70. Pubmed, doi:10.1103/physreva.49.2766. Full Text

Driehuys, B., et al. “Spin transfer between laser-polarized 129Xe nuclei and surface protons.” Physics Letters A, vol. 184, no. 1, Dec. 1993, pp. 88–92. Scopus, doi:10.1016/0375-9601(93)90352-Z. Full Text

Gatzke, M., et al. “Extraordinarily slow nuclear spin relaxation in frozen laser-polarized 129Xe.Phys Rev Lett, vol. 70, no. 5, Feb. 1993, pp. 690–93. Pubmed, doi:10.1103/PhysRevLett.70.690. Full Text