James T. Dobbins

Professor in Radiology

Office Location: 
Flowers Bldg, Suite 214, Box 90036, Durham, NC 27708
Front Office Address: 
Flowers Bldg, Suite 214, Box 90036, Durham, NC 27708
Phone: 
(919) 684-4859

Overview

James T. Dobbins III, PhD., FAAPM
Director, Medical Physics Graduate Program
Professor of Radiology, Biomedical Engineering, and Physics
Co-founder, Society of Directors of Academic Medical Physics Programs, Inc.

The research in my laboratory focuses on three main areas:  (1) advanced imaging applications to improve diagnostic accuracy in clinical imaging, (2) the scientific assessment of image quality, and (3) developing lower cost imaging for the developing world.

Projects in the area of advanced imaging applications have included applications of dual-energy and digital tomosynthesis for improving detection of cancer in chest and breast imaging.  We are the leading laboratory in the world in the application of tomosynthesis to thoracic imaging applications, and were the first to demonstrate that tomosynthesis can triple the detection sensitivity of pulmonary nodules over conventional chest radiography.  We have had four NIH R01 grants funded to develop, optimize, and perform clinical studies of dual-energy and tomosynthesis imaging; commercial products in both these modalities are now available around the world as a result of our laboratory’s efforts.

My lab’s work in the science of image quality analysis has included substantial effort in the theory and experimental measurement of modulation transfer function, noise power spectrum, and detective quantum efficiency in undersampled digital systems.  We received the Sylvia Sorkin Greenfield award in 1996 for the best publication of the year in the journal Medical Physics as a result of this work.

Current projects include the development of a new noise reduction technique called Correlated-Polarity Noise Reduction for improvement of image quality and reduction of dose in CT imaging, and the development of a lower-cost CT scanner for the developing world.

In addition to these research interests, I also serve as the Director of the Medical Physics Graduate Program at Duke, which includes over 50 faculty and 50 MS and PhD students training in diagnostic imaging physics, radiation oncology physics, nuclear medicine physics, and medical health physics.

Education & Training

  • Ph.D., University of Wisconsin at Madison 1985

  • M.S., University of Wisconsin at Madison 1983

  • B.S., University of North Carolina at Chapel Hill 1978

Training in Medical Imaging awarded by National Institutes of Health (Mentor). 2003 to 2019

Simulation Tools for 3D and 4D CT and Dosimetry awarded by National Institutes of Health (Investigator). 2007 to 2018

3D Digital Breast Phantoms For Multimodality Research awarded by National Institutes of Health (Investigator). 2010 to 2014

Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health (Principal Investigator). 2007 to 2013

Tomosynthesis for Improved Pulmonary Nodule Detection awarded by National Institutes of Health (Principal Investigator). 1999 to 2007

Dual-Energy Screening For Nodular Disease awarded by National Institutes of Health (Principal Investigator). 1998 to 2000

Dual Energy Screening For Nodular Disease awarded by National Institutes of Health (Principal Investigator). 1992 to 1999

Dual-Energy Screening For Nodular Disease awarded by National Institutes of Health (Principal Investigator). 1992 to 1996

Dual Energy Screening For Nodular Disease awarded by National Institutes of Health (Principal Investigator). 1993 to 1995

Dual-Energy Screening For Modular Disease awarded by National Institutes of Health (Principal Investigator). 1992 to 1995

Pages

Dobbins, JT, Frush, DP, Kigongo, CJN, MacFall, JR, Reiman, RE, Trahey, GE, Dobbins, JT, Frush, DP, Kigongo, CJN, MacFall, JR, Reiman, RE, and Trahey, GE. "Medical imaging safety in the developing worldMedical imaging safety in the developing world (PublishedPublished)." Radiology in Global Health: Strategies, Implementation, and Applications. October 1, 2014. 41-60. Full Text

Pawlicki, T, Ayers, RG, Brock, KK, Clements, JB, Curran, BH, Dobbins, JT, Samei, E, Adams, E, Martin, MC, and Schober, L. "Proposed changes to the American Association of Physicists in Medicine governance." Journal of applied clinical medical physics 18.4 (July 2017): 4-6. Full Text

Dobbins, JT, McAdams, HP, Sabol, JM, Chakraborty, DP, Kazerooni, EA, Reddy, GP, Vikgren, J, and Båth, M. "Multi-Institutional Evaluation of Digital Tomosynthesis, Dual-Energy Radiography, and Conventional Chest Radiography for the Detection and Management of Pulmonary Nodules." Radiology 282.1 (January 2017): 236-250. Full Text

Erickson, DW, Wells, JR, Sturgeon, GM, Samei, E, Dobbins, JT, Segars, WP, and Lo, JY. "Population of 224 realistic human subject-based computational breast phantoms." Medical physics 43.1 (January 2016): 23-. Full Text

Kiarashi, N, Lo, JY, Lin, Y, Ikejimba, LC, Ghate, SV, Nolte, LW, Dobbins, JT, Segars, WP, and Samei, E. "Development and application of a suite of 4-D virtual breast phantoms for optimization and evaluation of breast imaging systems." IEEE transactions on medical imaging 33.7 (July 2014): 1401-1409. Full Text

Dobbins, JT, Wells, JR, and Segars, WP. "Dose reduction in CT with correlated-polarity noise reduction: Context-dependent spatial resolution and noise properties demonstrating two-fold dose reduction with minimal artifacts." Progress in Biomedical Optics and Imaging - Proceedings of SPIE 9033 (January 1, 2014). Full Text

Hsu, CML, Palmeri, ML, Segars, WP, Veress, AI, and Dobbins, JT. "Generation of a suite of 3D computer-generated breast phantoms from a limited set of human subject data." Med Phys 40.4 (April 2013): 043703-. Full Text

Godfrey, DJ, McAdams, HP, and Dobbins, JT. "The effect of averaging adjacent planes for artifact reduction in matrix inversion tomosynthesis." Med Phys 40.2 (February 2013): 021907-. Full Text

III, JTD, Wells, JR, and Segars, WP. "Dose reduction in CT with correlated-polarity noise reduction: Comparable image quality at half the dose with projection space processing." Progress in Biomedical Optics and Imaging - Proceedings of SPIE 8668 (2013). Full Text

Wells, JR, and III, JTD. "Preliminary investigation of the frequency response and distortion properties of nonlinear image processing algorithms." Progress in Biomedical Optics and Imaging - Proceedings of SPIE 8668 (2013). Full Text

Pages

Segars, WP, Veress, AI, Wells, JR, Sturgeon, GM, Kiarashi, N, Lo, JY, Samei, E, and Dobbins, JT. "Population of 100 realistic, patient-based computerized breast phantoms for multi-modality imaging research." January 1, 2014. Full Text

Kiarashi, N, Sturgeon, GM, Nolte, LW, Lo, JY, III, JTD, Segars, WP, and Samei, E. "Development of matched virtual and physical breast phantoms based on patient data." 2013. Full Text

Kiarashi, N, Lin, Y, Segars, WP, Ghate, SV, Ikejimba, L, Chen, B, Lo, JY, Iii, JTD, Nolte, LW, and Samei, E. "Development of a dynamic 4D anthropomorphic breast phantom for contrast-based breast imaging." 2012. Full Text

III, DJT, Wells, JR, Segars, WP, Li, CM, and Kigongo, CJN. "Initial investigation into lower-cost CT for resource limited regions of the world." 2010. Full Text

Hendee, W, Giger, M, Starkschall, G, Molloy, J, Peroni, C, Seibert, J, Dobbins, J, Smilowitz, J, Hogstrom, K, Montemayor, V, and Jackson, E. "TU-C-211A-01: Becoming a Better Teacher." June 2009. Full Text

Pages