Ehsan Samei

Professor of Radiology

External Address: 
2424 Erwin Road, Suite 302, Ravin Advanced Imaging Labs, Durham, NC 27705
Internal Office Address: 
DUMC Box 2731, Durham, NC 27710
(919) 684-7852


Dr. Ehsan Samei, PhD, DABR, FAAPM, FSPIE is a tenured Professor of Radiology, Medical Physics, Biomedical Engineering, Physics, and Electrical and Computer Engineering at Duke University, where he also serves as the Director of Carl E. Ravin Advanced Imaging Laboratories and the founding Chief of the Clinical Imaging Physics Group. He is certified by the American Board of Radiology, and is a Fellow of the American Association of Physicists in Medicine (AAPM), and the International Society of Optical Engineering (SPIE). He was the founding Director of the Graduate Studies of the Duke Medical Physics Graduate Program, and the co-founder of the Society of Directors of Academic Medical Physics Programs (SDAMPP). He has held senior leadership positions in the AAPM, the SPIE, and SDAMPP. He is a Councilor of the National Council of Radiation Protection and Measurements (NCRP), and a Distinguished Investigator of the Academy of Radiology Research.

Dr. Samei’s interests and expertise include x-ray imaging, theoretical imaging models, simulation methods, and experimental techniques in medical image formation, analysis, assessment, display, and perception. His current research includes methods to develop image quality and dose metrics that are clinically relevant and that can be used to design and utilize advanced imaging techniques towards precise interpretive and quantitative performance. He further has an active interest in bridging the gap between scientific scholarship and clinical practice, in the meaningful realization of translational research and in clinical processes that are informed by scientific evidence. While he works across most diagnostic imaging modalities, his main modalities of interest are CT and Tomosynthesis for breast, lung, and abdominal imaging applications. He has been the recipient of 29 extramural grants from the US government, private foundations, and medical industry, and has 700 scientific publications including 190 referred journal articles.

Education & Training

  • Ph.D., University of Michigan at Ann Arbor 1997

  • M.E., University of Michigan at Ann Arbor 1995

Precision Cardiac CT: Development of a Computational Platform for Optimizing Imaging awarded by National Institutes of Health (Principal Investigator). 2017 to 2021

Training in Medical Imaging awarded by National Institutes of Health (Mentor). 2003 to 2019

Simulation Tools for 3D and 4D CT and Dosimetry awarded by National Institutes of Health (Co-Principal Investigator). 2007 to 2018

Imaging Physics Residency Grant awarded by American Association of Physicists in Medicine (Principal Investigator). 2014 to 2018

Reconstruction Software Evaluation awarded by Siemens Medical Solutions USA, Inc. (Principal Investigator). 2014 to 2018

Methodology and Reference Image set for Volumetric Characterization and Compliance awarded by Radiological Society of North America (Principal Investigator). 2014 to 2017

Reference Image Set for Quantitation Conformance of Algorithmic Lesion Characterization awarded by Radiological Society of North America (Principal Investigator). 2014 to 2017

Advancement and Effective Implementation of Dose and Risk Monitoring Systems awarded by GE Healthcare (Principal Investigator). 2014 to 2017

Decreased Variability for Robust Imaging-based Quantification of Tumor Heterogeneity awarded by Radiological Society of North America (Advisor). 2015 to 2017

IAEA scientific visit and training awarded by International Atomic Energy Agency (Principal Investigator). 2016


Sahbaee, P, Abadi, E, Segars, WP, Marin, D, Nelson, RC, and Samei, E. "The Effect of Contrast Material on Radiation Dose at CT: Part II. A Systematic Evaluation across 58 Patient Models." Radiology 283.3 (June 2017): 749-757. Full Text

Sahbaee, P, Segars, WP, Marin, D, Nelson, RC, and Samei, E. "The Effect of Contrast Material on Radiation Dose at CT: Part I. Incorporation of Contrast Material Dynamics in Anthropomorphic Phantoms." Radiology 283.3 (June 2017): 739-748. Full Text

Bellini, D, Ramirez-Giraldo, JC, Bibbey, A, Solomon, J, Hurwitz, LM, Farjat, A, Mileto, A, Samei, E, and Marin, D. "Dual-Source Single-Energy Multidetector CT Used to Obtain Multiple Radiation Exposure Levels within the Same Patient: Phantom Development and Clinical Validation." Radiology 283.2 (May 2017): 526-537. Full Text

Zhang, Y, Smitherman, C, and Samei, E. "Size-specific optimization of CT protocols based on minimum detectability." Medical physics 44.4 (April 2017): 1301-1311. Full Text

Mileto, A, Nelson, RC, Larson, DG, Samei, E, Wilson, JM, Christianson, O, Marin, D, and Boll, DT. "Variability in Radiation Dose From Repeat Identical CT Examinations: Longitudinal Analysis of 2851 Patients Undergoing 12,635 Thoracoabdominal CT Scans in an Academic Health System." AJR. American journal of roentgenology (March 28, 2017): 1-12. Full Text

Fu, W, Tian, X, Sturgeon, GM, Agasthya, G, Segars, WP, Goodsitt, MM, Kazerooni, EA, and Samei, E. "CT breast dose reduction with the use of breast positioning and organ-based tube current modulation." Medical physics 44.2 (February 2017): 665-678. Full Text

Sanders, J, Tian, X, Segars, WP, Boone, J, and Samei, E. "Automated, patient-specific estimation of regional imparted energy and dose from tube current modulated computed tomography exams across 13 protocols." Journal of medical imaging (Bellingham, Wash.) 4.1 (January 24, 2017): 013503-. Full Text

Mileto, A, and Samei, E. "Hallway Conversations in Physics." AJR. American journal of roentgenology 208.1 (January 2017): W24-W27. (Review) Full Text


Robins, M, Solomon, J, Hoye, J, Smith, T, Ebner, L, and Samei, E. "Inter-algorithm lesion volumetry comparison of real and 3D simulated lung lesions in CT." January 1, 2017. Full Text

Zhao, C, Solomon, J, Sturgeon, GM, Gehm, ME, Catenacci, M, Wiley, BJ, Samei, E, and Lo, JY. "Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region." January 1, 2017. Full Text

Hoye, J, Zhang, Y, Agasthya, G, Sturgeon, G, Kapadia, A, Segars, WP, and Samei, E. "An atlas-based organ dose estimator for tomosynthesis and radiography." January 1, 2017. Full Text

Fu, W, Sturgeon, GM, Agasthya, G, Segars, WP, Kapadia, AJ, and Samei, E. "Estimation of breast dose reduction potential for organ-based tube current modulated CT with wide dose reduction arc." January 1, 2017. Full Text

Abadi, E, Sturgeon, GM, Agasthya, G, Harrawood, B, Hoeschen, C, Kapadia, A, Segars, WP, and Samei, E. "Airways, vasculature, and interstitial tissue: Anatomically informed computational modeling of human lungs for virtual clinical trials." January 1, 2017. Full Text

Zheng, Y, Solomon, J, Choudhury, K, Marin, D, and Samei, E. "Accuracy and variability of texture-based radiomics features of lung lesions across CT imaging conditions." January 1, 2017. Full Text