Ehsan Samei

Ehsan Samei

Professor of Radiology

Office Location: 
2424 Erwin Road, Suite 302, Ravin Advanced Imaging Labs, Durham, NC 27705
Front Office Address: 
DUMC Box 2731, Durham, NC 27710
(919) 684-7852


Dr. Ehsan Samei, PhD, DABR, FAAPM, FSPIE, FAIMBE is a Persian-American medical physicist. He is a tenured Professor of Radiology, Medical Physics, Biomedical Engineering, Physics, and Electrical and Computer Engineering at Duke University. He serves as the Director of the Duke Medical Physics Graduate Program and the Director of the Clinical Imaging Physics Group. He is certified by the American Board of Radiology, and is a Fellow of the American Association of Physicists in Medicine (AAPM), the International Society of Optics and Phtonics (SPIE), and the American Institute of Biomedical Engineering. He is a Councilor of the National Council of Radiation Protection and Measurements (NCRP), and a Distinguished Investigator of the Academy of Radiology Research. He was the founder or co-founder of the Duke Medical Physics Program, the Duke Imaging Physics Residency Program, the Duke Clinical Imaging Physics Group, and the Society of Directors of Academic Medical Physics Programs (SDAMPP). He has held senior leadership positions in the AAPM, SPIE, SDAMPP, and RSNA. 

Dr. Samei’s interests and expertise include x-ray imaging, theoretical imaging models, simulation methods, and experimental techniques in medical image formation, analysis, assessment, and perception.  His current research includes methods to develop image quality and dose metrics that are clinically relevant and that can be used to design and utilize advanced imaging techniques towards optimum interpretive and quantitative performance. He further has an active interest in bridging the gap between scientific scholarship and clinical practice, in the meaningful realization of translational research, and in clinical processes that are informed by scientific evidence. Those include advanced imaging performance characterization, procedural optimization, and radiomics in retrospective clinical dose and quality analytics. He has mentored over 100 trainees (graduate and postgraduate). He has over 900 scientific publications including over 240 referred journal articles. He has been the recipient of 34 grants as Principle Investigator reflecting $13M of extramural funding.

Education & Training

  • Ph.D., University of Michigan at Ann Arbor 1997

  • M.E., University of Michigan at Ann Arbor 1995

Selected Grants

Precision Cardiac CT: Development of a Computational Platform for Optimizing Imaging awarded by National Institutes of Health (Principal Investigator). 2017 to 2021

Physics Associates Affiliate Residency Program awarded by Physics Associates (Principal Investigator). 2017 to 2020

3D Printing of Anatomically Realistic Phantoms for Optimization of Imaging Algorithms awarded by National Institutes of Health (Co Investigator). 2018 to 2020

Training in Medical Imaging awarded by National Institutes of Health (Mentor). 2003 to 2019

Simulation Tools for 3D and 4D CT and Dosimetry awarded by National Institutes of Health (Co-Principal Investigator). 2007 to 2018

Imaging Physics Residency Grant awarded by American Association of Physicists in Medicine (Principal Investigator). 2014 to 2018

Reconstruction Software Evaluation awarded by Siemens Medical Solutions USA, Inc. (Principal Investigator). 2014 to 2018

Methodology and Reference Image set for Volumetric Characterization and Compliance awarded by Radiological Society of North America (Principal Investigator). 2014 to 2017

Reference Image Set for Quantitation Conformance of Algorithmic Lesion Characterization awarded by Radiological Society of North America (Principal Investigator). 2014 to 2017

Advancement and Effective Implementation of Dose and Risk Monitoring Systems awarded by GE Healthcare (Principal Investigator). 2014 to 2017


Smith, TB, Solomon, J, and Samei, E. "Estimating detectability index in vivo: development and validation of an automated methodology. (Accepted)" Journal of Medical Imaging 5.3 (July 2018): 031403-. Full Text

Samei, E, Robins, M, Chen, B, and Agasthya, G. "Estimability index for volume quantification of homogeneous spherical lesions in computed tomography. (Accepted)" Journal of Medical Imaging 5.3 (July 2018): 031404-. Full Text

Abadi, E, Segars, WP, Sturgeon, GM, Roos, JE, Ravin, CE, and Samei, E. "Modeling Lung Architecture in the XCAT Series of Phantoms: Physiologically Based Airways, Arteries and Veins." IEEE transactions on medical imaging 37.3 (March 2018): 693-702. Full Text

Samei, E, Ikejimba, LC, Harrawood, BP, Rong, J, Cunningham, IA, and Flynn, MJ. "Report of AAPM Task Group 162: Software for planar image quality metrology." Medical physics 45.2 (February 2018): e32-e39. Full Text

Richards, T, Sturgeon, GM, Ramirez-Giraldo, JC, Rubin, GD, Koweek, LH, Segars, WP, and Samei, E. "Quantification of uncertainty in the assessment of coronary plaque in CCTA through a dynamic cardiac phantom and 3D-printed plaque model." Journal of medical imaging (Bellingham, Wash.) 5.1 (January 17, 2018): 013501-. Full Text

Samei, E, Tian, X, Paul Segars, W, and Frush, DP. "Radiation risk index for pediatric CT: a patient-derived metric." Pediatric radiology 47.13 (December 2017): 1737-1744. Full Text

Abadi, E, Sahbaee, P, and Samei, E. "Effect of Iodine-based Contrast Material on Radiation Dose at CT." Radiology 285.3 (December 2017): 1053-1054. Full Text

Winslow, J, Zhang, Y, and Samei, E. "A method for characterizing and matching CT image quality across CT scanners from different manufacturers." Medical physics 44.11 (November 2017): 5705-5717. Full Text

Ria, F, Bergantin, A, Vai, A, Bonfanti, P, Martinotti, AS, Redaelli, I, Invernizzi, M, Pedrinelli, G, Bernini, G, Papa, S, and Samei, E. "Awareness of medical radiation exposure among patients: A patient survey as a first step for effective communication of ionizing radiation risks." Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) 43 (November 2017): 57-62. Full Text

Fu, W, Marin, D, Ramirez-Giraldo, JC, Choudhury, KR, Solomon, J, Schabel, C, Patel, BN, and Samei, E. "Optimizing window settings for improved presentation of virtual monoenergetic images in dual-energy computed tomography." Medical physics 44.11 (November 2017): 5686-5696. Full Text


Zhao, C, Solomon, J, Sturgeon, GM, Gehm, ME, Catenacci, M, Wiley, BJ, Samei, E, and Lo, JY. "Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region." January 1, 2017. Full Text

Hoye, J, Zhang, Y, Agasthya, G, Sturgeon, G, Kapadia, A, Segars, WP, and Samei, E. "An atlas-based organ dose estimator for tomosynthesis and radiography." January 1, 2017. Full Text

Fu, W, Sturgeon, GM, Agasthya, G, Segars, WP, Kapadia, AJ, and Samei, E. "Estimation of breast dose reduction potential for organ-based tube current modulated CT with wide dose reduction arc." January 1, 2017. Full Text

Abadi, E, Sturgeon, GM, Agasthya, G, Harrawood, B, Hoeschen, C, Kapadia, A, Segars, WP, and Samei, E. "Airways, vasculature, and interstitial tissue: Anatomically informed computational modeling of human lungs for virtual clinical trials." January 1, 2017. Full Text

Zheng, Y, Solomon, J, Choudhury, K, Marin, D, and Samei, E. "Accuracy and variability of texture-based radiomics features of lung lesions across CT imaging conditions." January 1, 2017. Full Text

Richards, T, Sturgeon, GM, Ramirez-Giraldo, JC, Rubin, G, Segars, P, and Samei, E. "Quantification of the uncertainty in coronary CTA plaque measurements using dynamic cardiac phantom and 3D-printed plaque models." January 1, 2017. Full Text